Genetic Engineering Publications - GEG Tech top picks
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The CRISPR/Cas system inhibited the pro-oncogenic effects of alternatively spliced fibronectin extra domain A via editing the genome in salivary adenoid cystic carcinoma cells

The CRISPR/Cas system inhibited the pro-oncogenic effects of alternatively spliced fibronectin extra domain A via editing the genome in salivary adenoid cystic carcinoma cells | Genetic Engineering Publications - GEG Tech top picks | Scoop.it
From onlinelibrary.wiley.com - February 19, 2015 11:39 AM

To identify the association of fibronectin (FN) extra domain A (EDA) with the progression of salivary adenoid cystic carcinoma (SACC). Accordingly, the exclusion of EDA exon through the CRISPR/Cas9 system was investigated as the rescue for such pro-oncogenic splicing.

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Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model | Genetic Engineering Publications - GEG Tech top picks | Scoop.it
December 9, 2013 4:25 AM

http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2847.html

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An original use of a transposon to better understand the hepatocarcinoma mechanisms.

 

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BigField GEG Tech's curator insight, December 9, 2013 5:29 AM

An original use of a transposon to better understand the hepatocarcinoma mechanisms.

 

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